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丹麦科技大学国家兽医研究所(DTU VET)分子生物学博士职位

DTU VET is part of the Technical University of Denmark. The Institute conducts research, provides education and gives advice on infectious animal diseases in farm livestock and companion animals. Daily work will be performed at the Department of Poultry, Fish and Fur Animals located in Aarhus. Here, the Section for Fish Diseases focuses on viral diseases, vaccinology and immunology in fish.

The PhD scholar will contribute to the project “Identification of virulence markers in marine VHS virus and use in diagnostics for aquaculture” funded by The Danish Research Council for Technology and Production Sciences (FTP).

Production of rainbow trout in marine aquaculture is an expanding industry in Denmark, but a circulating reservoir of the fish pathogenic viral haemorrhagic septicaemia virus (VHSV) in wild fish populations represents an important threat towards the future success of these activities.

The primary task of the PhD scholar will be to determine the genetic background for virulence of VHSV isolates to rainbow trout. Various molecular tools will be applied such as reverse genetics for generation of recombinant virus, in vivo imaging and immunofluorescense for in situ pathogenesis studies as well as virulence testing in small scale animal experiments. The expected result will be improved understanding of pathogen virulence and identification of genetic markers for virulence of VHSV isolates in rainbow trout. The obtained results will be used for development of a diagnostic tool for rapid virulence-typing of VHSV isolates.

Preferred qualifications
• good experience in practical research
• a master’s degree (M.Sc.) in biology or a similar degree
• ability to work with animal experiments
• ability to design and perform research work plans on an individual basis as well as a team-member
• good routine in English, speaking, reading and writing
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